Please ensure Javascript is enabled for purposes of website accessibility
Contact us Contact Us
EN
Home > Featured Products > Neuroscience > Fibromyalgia / Chronic Widespread Pain

Fibromyalgia & Chronic Widespread Pain Research Reagents

abinScience provides high-quality recombinant neurotrophins (BDNF, NGF), pro-inflammatory cytokines, glial activation markers and in vivo-grade blocking antibodies for fibromyalgia and chronic widespread pain research, focusing on central sensitization, glial activation and neuro-immune interactions (acid-saline, reserpine, chronic stress models). Every lot released with detailed CoA. For research use only (RUO).

Shop by target

Shop by product type

Selection guide

  1. Neurotrophins: Elevated BDNF/NGF in CSF of fibromyalgia patients → use in vivo-grade anti-NGF or anti-TrkA for pain reversal studies.
  2. Neuroinflammation: Spinal microglia (Iba1) and astrocyte (GFAP) activation; cytokines (IL-6, IL-8) in plasma/CSF.
  3. Central sensitization: Phospho-NR1 and pERK in dorsal horn as mechanistic readouts.
  4. Models: Repeated acid-saline IM injection, reserpine-induced, chronic stress — all show widespread mechanical allodynia.
  5. Biomarkers: S100B and cytokine panels in patient serum; translate with validated ELISA.

Spotlight

 

Anti-NGF (mAb) — In Vivo Grade

Endotoxin <0.01 EU/µg • Reversal of widespread pain in models

 

Anti-GFAP — Astrocyte Marker

Robust staining in fibromyalgia-like models

 

IL-6 / IL-8 Duplex ELISA Kit (RUO)

pg/mL sensitivity • Plasma & CSF validated

FAQs

Why is anti-NGF promising for fibromyalgia?

NGF is dramatically elevated in patient CSF; anti-NGF antibodies (e.g., tanezumab phase studies) reverse widespread pain in preclinical models and showed efficacy in clinical trials.

Glial activation in fibromyalgia?

Spinal microglia and astrocytes drive central sensitization via cytokine release; Iba1/GFAP upregulation is a hallmark of fibromyalgia-like pain states.

Are these products for clinical use?

All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic procedures.

21 product results for "Fibromyalgia / Chronic Widespread Pain"

Options+
Options
Confirm
  • Product types
    0 selected
    Antibodies (14)
    Proteins (7)
  • Expression system
    0 selected
    Mammalian Cells (1)
    E. coli (6)
  • Target
    0 selected
    SLC6A4/SERT (3)
    HTR2A (3)
    COMT (2)
    GRM5 (2)
    BDNF (10)
  • Species
    0 selected
    Human (7)
    Mouse (1)
    Homo sapiens (Human) (1)
    Rat (1)
    Dog (1)
    Horse (1)
    Bovine (1)
    Pig (1)
  • Applications
    0 selected
    IF (1)
    WB (10)
    IHC (3)
    IP (1)
    Blocking (2)
    SDS-PAGE (7)
    Immunogen (7)
    Bioactivity testing in progress (6)
    ELISA (20)
    Neutralization (1)
    FCM (7)
  • Reactivity
    0 selected
    Anilius scytale (1)
    Xenopus laevis (1)
    Loxocemus bicolor (1)
    Chilabothrus striatus (1)
    Rat (1)
    Eryx jayakari (1)
    Aspidites melanocephalus (1)
    Xiphophorus maculatus (1)
    Macaca mulatta (1)
    Corallus caninus (1)
    Mouse (1)
    Sanzinia madagascariensis (1)
    Eryx johnii (1)
    Boa constrictor (1)
    Macrovipera lebetinus (1)
    Cylindrophis ruffus (1)
    Dog (1)
    Spermophilus citellus (1)
    Eunectes notaeus (1)
    Exiliboa placata (1)
    Bos taurus (1)
    Morelia spilota (1)
    Cyprinus carpio (1)
    Cat (1)
    Pig (1)
    Chicken (1)
    Calabaria reinhardtii (1)
    Pan troglodytes (1)
    Human (12)
    Epicrates cenchria (1)
    Acrantophis dumerili (1)
    Tropidophis haetianus (1)
    Helarctos malayanus (1)
    Candoia carinata (1)
    Procyon lotor (1)
    Equus caballus (1)
    Acrochordus javanicus (1)
    Ursus arctos (1)
    Ursus thibetanus (1)
    Lichanura trivirgata (1)
    Cavia porcellus (1)
    Ptyas major (1)
    Eryx colubrinus colubrinus (1)
    Ailuropoda melanoleuca (1)
    Ailurus fulgens (1)
    Xenopeltis unicolor (1)
    Lipotes vexillifer (1)
    Homo sapiens (Human) (1)
    Charina bottae (1)
    Ramphotyphlops sp. (1)
    Eryx conicus (1)
  • Host species
    0 selected
    Mouse (7)
    Alpaca (3)
    Rabbit (3)
    Human (1)
  • Clonality
    0 selected
    Monoclonal (11)
    Polyclonal (3)
  • Conjugate
    0 selected
    Unconjugated (7)
    FITC (1)
    APC (1)
    PerCP (1)
    PE (1)

Quick access

Contact Us

  • +86-027-65523339

  • info@abinscience.com

  • Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China

Copyright © 2025 abinScience. All Rights Reserved. All Products are for Research Use Only