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Schizophrenia Research Reagents

abinScience provides high-quality recombinant proteins (DISC1, NRG1, Reelin, dysbindin), validated antibodies targeting GABAergic interneuron markers (GAD67, parvalbumin) and dopamine receptors for schizophrenia research (DISC1, DFNB, maternal immune activation, and pharmacological models). Every lot released with detailed CoA. For research use only (RUO).

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Selection guide

  1. Neurodevelopmental hypothesis: DISC1, NRG1/ErbB4, Reelin, dysbindin for migration and synaptic maturation.
  2. GABAergic interneuron deficit: GAD67, parvalbumin (PV), Reelin antibodies for inhibitory circuitry studies.
  3. Dopamine hypothesis: DRD2 antibodies and ligands for antipsychotic target validation.
  4. Animal models: DISC1 mutants, maternal polyI:C, NMDA antagonists (MK-801, ketamine).
  5. Behavioral readouts: PPI, LI, social interaction, working memory tasks.

Spotlight

 

DISC1 Recombinant Protein

Validated interaction with NDEL1 • Purity ≥95%

 

Anti-GAD67 (mAb) — Interneuron Marker

High specificity • IHC & WB validated in models

 

Anti-Parvalbumin — PV Interneurons

Robust staining • Low background in cortex/hippocampus

FAQs

GAD67 vs parvalbumin for interneuron studies?

GAD67 labels all GABAergic interneurons; parvalbumin selectively marks fast-spiking basket/chandelier cells most affected in schizophrenia.

Which model best recapitulates schizophrenia endophenotypes?

Acute/subchronic NMDA antagonists (MK-801, ketamine) for positive symptoms & cognitive deficits; DISC1 mutants and developmental models (polyI:C) for neurodevelopmental aspects.

Are these products for clinical use?

All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic procedures.

29 product results for "Schizophrenia"

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  • Product types
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    Proteins (12)
    Antibodies (17)
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    E. coli (9)
    Mammalian Cells (3)
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    GRIN1/NMDAR1 (6)
    DRD2 (8)
    GRIN2A (4)
    C4A/Complement C4-A (1)
    C4b/Complement C4b (2)
    C4a anaphylatoxin (1)
    GAD1/GAD67 (2)
    COMT (2)
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    Homo sapiens (Human) (3)
    Human (9)
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    Bioactivity testing in progress (9)
    ELISA (28)
    FCM (5)
    WB (20)
    Blocking (2)
    IHC (7)
    SDS-PAGE (12)
    Immunogen (12)
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    Dog (1)
    Human (17)
    Rat (6)
    Bos taurus (1)
    Chlorocebus aethiops (1)
    Mustela putorius furo (1)
    Xenopus laevis (1)
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    Mouse (5)
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    Mouse (2)
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    Rabbit (6)
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    Monoclonal (11)
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  • Conjugate
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    PerCP (1)
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