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Autism Spectrum Disorder Research Reagents

abinScience provides high-quality recombinant synaptic scaffolding proteins (Shank3, Neuroligin/Neurexin), oxytocin, mTOR pathway components and validated antibodies for autism spectrum disorder research, covering synaptic dysfunction, social behavior deficits and repetitive behavior models. Every lot includes detailed CoA. For research use only (RUO).

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Selection guide

  1. Synaptic hypothesis: Shank3, Neuroligin/Neurexin for excitatory synapse formation and social behavior.
  2. Social neuropeptide: Oxytocin and OXTR antibodies/receptors for social reward and recognition studies.
  3. mTOR hyperactivation: PTEN, TSC1/2 knockout models → use phospho-S6, mTOR antibodies.
  4. E/I imbalance: GABA receptor subunits and interneuron markers.
  5. Behavioral assays: Three-chamber social test, marble burying, ultrasonic vocalization, self-grooming.

Spotlight

 

Shank3 Recombinant Protein

PSD-95 interaction validated • Purity ≥95%

 

Anti-Oxytocin (mAb)

IHC & ELISA validated • Low background

 

Oxytocin ELISA Kit (RUO)

pg/mL sensitivity • Plasma & tissue validated

FAQs

Shank3 vs Neuroligin/Neurexin for synaptic studies?

Shank3 is postsynaptic scaffolding (PSD); Neuroligin/Neurexin are trans-synaptic adhesion molecules — complementary for excitatory synapse maturation.

Is oxytocin a viable therapeutic target in ASD?

Intranasal oxytocin shows promise in some social cognition trials; reagents support mechanistic and biomarker studies.

Are these products approved for clinical use?

All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic procedures.

2 product results for "Autism Spectrum Disorder"

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