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Ischemic Stroke Research Reagents

abinScience provides high-quality recombinant proteins (tPA, NMDA/AMPA subunits, MMP-9), validated antibodies and ultra-sensitive neurofilament light (NfL) ELISA kits for ischemic stroke research, covering excitotoxicity, BBB breakdown, thrombolysis and reperfusion injury (MCAO, tMCAO, photothrombosis models). Every lot released with detailed CoA. For research use only (RUO).

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Selection guide

  1. Excitotoxicity: NMDA (NR1/NR2B) and AMPA receptor subunits for glutamate-mediated injury.
  2. Thrombolysis & hemorrhage: Recombinant tPA and MMP-9 antibodies for reperfusion injury studies.
  3. BBB integrity: Tight junction proteins (Claudin-5, Occludin, ZO-1) loss after ischemia.
  4. Neuroaxonal damage marker: NfL in plasma/CSF as stroke severity and outcome biomarker.
  5. Neuroinflammation: Microglia (Iba1) and astrocyte (GFAP) activation.

Spotlight

 

tPA Recombinant, Active

Enzymatically active • Endotoxin <0.01 EU/µg • MCAO validated

 

Anti-NMDA NR2B (mAb)

High affinity • WB/IHC/functional blocking

 

Neurofilament Light (NfL) ELISA Kit (RUO)

fg/mL sensitivity • Plasma & CSF validated

FAQs

Why is NfL a promising stroke biomarker?

NfL rises rapidly in blood after ischemic injury, correlates with infarct volume and functional outcome, and is applicable in preclinical and clinical studies.

tPA recombinant vs commercial clinical-grade?

Our research-grade tPA is enzymatically active, ultra-low endotoxin, and optimized for preclinical MCAO/reperfusion models.

Are these products for clinical use?

All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic procedures.

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