| Catalog No. | HB016016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Humanized |
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| Isotype | IgG4-Kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | IL7R, Interleukin-7 receptor subunit alpha, IL-7R-alpha, IL-7 receptor subunit alpha, CD127, CDw127, IL-7R subunit alpha, IL-7RA |
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| Concentration | 1mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | P16871 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -698°C. |
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| Alternate Names | Effi-7,Effi7-h,MD-707,CAS:2375835-91-7 |
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| Background | Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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