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Certolizumab ELISA Kit (DF879028)

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Overview
Catalog No.DF879028
Sample typePlasma, Serum
Sensitivity329.66 ng/mL
Range468.75 - 30,000 ng/mL
AccessionP01375
ApplicationsELISA
Detection methodColorimetric
Assay typeQuantitative
Recovery80-120%
Shipping2-8 ℃
Stability and StorageWhen the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20 ℃, the rest reagents should be store at 4℃.
SpecificationsCertolizumab
Alternate NamesCDP870, PHA-738144, Certolizumab pegol, CAS: 428863-50-7
BackgroundCertolizumab pegol is a recombinant, humanized F(ab)’ fragment of an antibody conjugated to polyethylene glycol to enhance its plasma half-life. It does not contain an FC region and therefore does not cause antibody-dependent cell-mediated or complement-dependent cytotoxicity as described for infliximab, etanercept, and adalimumab. Another difference is that certolizumab pegol preferentially penetrates inflamed tissue compared to noninflamed tissue, and does so to a greater extent than adalimumab or infliximab. It is directed against soluble and membrane-associated human TNF-α and was approved for the treatment of Crohn’s disease that does not respond to conventional therapy in 2008 and for RA in 2009.
NoteFor Research Use Only.
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