| Catalog No. | VK446023 |
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| Description | mAb 77 effectively neutralizes MeV infection in vitro and significantly reduces viral replication and loads in vivo in the cotton rat model. Mechanistic assays revealed that mAb 77 prevents the completion of membrane fusion, but does so without inhibiting F protein activation, fusion initiation, or the formation of the extended intermediate. |
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| Species reactivity | Measles virus (MeV) |
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| Applications | Neutralization, in vivo |
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| Host species | Mouse |
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| Isotype | IgG2a, kappa |
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| Clone ID | mAb 77 |
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| Clonality | Monoclonal |
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| Target | F/fusion protein |
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| Endotoxin level | Please contact with the lab for this information. |
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| Purity | >90% as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P69353 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
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| Alternate Names | Fusion glycoprotein F0, Fusion glycoprotein F2, Fusion glycoprotein F1, F |
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| Note | For research use only. |
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