| Catalog No. | HX065016 |
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| Species reactivity | Human |
|---|
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG1-Kappa |
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| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1 |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
Q01973 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | cirmtuzumab, 2485779-13-1 |
|---|
| Background | Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling.
• Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases., PMID:32619402
• SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression., PMID:34599596
• Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors., PMID:7838158
|
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| Note |
For research use only. Not suitable for clinical or therapeutic use. |
