| Catalog No. | HV777016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG1-kappa |
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| Expression system |
Mammalian Cells |
| Clonality |
Monoclonal |
| Target |
Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib |
| Endotoxin level |
Please contact the lab for this information. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Accession |
Q8TF66 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternate Names | ABBV-085, PR-1498487-MMAE, PR-1498487, Samrotamabvedotin, 2052591-32-7 |
|---|
| Background | Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15.
• A novel member of the leucine-rich repeat superfamily induced in rat astrocytes by beta-amyloid., PMID:11785964
• Mediators of inflammation and regeneration., PMID:21677081
• Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix., PMID:16098915
• High lib mRNA expression in breast carcinomas., PMID:15368894
|
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| Note |
For research use only. Not suitable for clinical or therapeutic use. |
