| Catalog No. | HB714036 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Chimeric |
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| Isotype | IgG1-kappa/scFv-h-CH2-CH3 |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | IL-3R subunit alpha, IL-3 receptor subunit alpha, CD123, Interleukin-3 receptor subunit alpha, IL3R, IL-3R-alpha, IL3RA, IL-3RA, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
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| Concentration | 1mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | P26951 & P07766 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -151°C. |
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| Alternate Names | Bispecific,XmAb14045,CAS:2138442-13-2 |
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| Background | Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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