| Catalog No. | HV684016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Humanized |
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| Isotype | (scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | MUC-3, MUC-17, MUC17, Small intestinal mucin-3, Mucin-17, MUC3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
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| Concentration | 1mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | Q685J3 & P07766 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -734°C. |
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| Alternate Names | Bispecific,AMG199,AMG-199,AMG199CAS:2413453-53-7 |
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| Background | Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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