Catalog No. | HV612046 |
---|---|
Species reactivity | Human |
Applications | Research Grade Biosimilar |
Host species | Humanized |
Isotype | scFv with Domain Crossover,Kappa;Lambda |
Expression system | Mammalian Cells |
Clonality | Monoclonal |
Target | CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
Concentration | 1.24mg/ml |
Endotoxin level | Please contact the lab for this information. |
Purity | >95% purity as determined by SDS-PAGE. |
Purification | Protein A/G, purified from cell culture supernatant. |
Accession | Q5ZPR3 & P07766 |
Form | Liquid |
Storage buffer | 0.01M PBS,pH7.4. |
Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -687°C. |
Alternate Names | Bispecific,MGD009,RES281M1.1,hBRCA84D-hXR32-MP3M1.1,CAS:2069959-72-2 |
Background | Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer. |
Note | For research use only. Not for use in clinical or therapeutic applications. |
SDS-PAGE for Research Grade Obrindatamab
Detects CD276 in indirect ELISAs.
Detects CD3E in indirect ELISAs.
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