Catalog No. | HC598016 |
---|---|
Species reactivity | Human |
Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
Host species | Human |
Isotype | IgG1-kappa |
Expression system | Mammalian Cells |
Clonality | Monoclonal |
Target | CLEC5B, KLRB1, CD161, HNKR-P1a, C-type lectin domain family 5 member B, NKRP1A, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1, NKR-P1A |
Endotoxin level | Please contact the lab for this information. |
Purity | >95% purity as determined by SDS-PAGE. |
Purification | Protein A/G purified from cell culture supernatant. |
Accession | Q12918 |
Form | Liquid |
Storage buffer | 0.01M PBS, pH 7.4. |
Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
Alternate Names | 2762201-86-3 |
Background | Rezorstobart is an anti-KLRB1 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). • Biological and Clinical Significance of Human NKRP1A/LLT1 Receptor/Ligand Interactions., PMID:31002602 • LLT1-CD161 Interaction in Cancer: Promises and Challenges., PMID:35185935 • A Role of NKR-P1A (CD161) and Lectin-like Transcript 1 in Natural Cytotoxicity against Human Articular Chondrocytes., PMID:29212911 • Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A., PMID:25826155 • CD161 (human NKR-P1A) signaling in NK cells involves the activation of acid sphingomyelinase., PMID:16455998 • Molecular basis for LLT1 protein recognition by human CD161 protein (NKRP1A/KLRB1)., PMID:21572041 • Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes., PMID:8077657 • Nkrp1 family, from lectins to protein interacting molecules., PMID:25690298 • Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction., PMID:27626681 • NKRP1A molecule is involved in transendothelial migration of CD4+ human T lymphocytes., PMID:9232437 |
Note | For research use only. Not suitable for clinical or therapeutic use. |
+33(0)3 90 20 54 70
19 rue de la Haye 67300 Schiltigheim France