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Research Grade Rezorstobart (HC598016)

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  • 100ug
  • 1mg
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Overview
Catalog No.HC598016
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetCLEC5B, KLRB1, CD161, HNKR-P1a, C-type lectin domain family 5 member B, NKRP1A, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1, NKR-P1A
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionQ12918
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names2762201-86-3
BackgroundRezorstobart is an anti-KLRB1 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
• Biological and Clinical Significance of Human NKRP1A/LLT1 Receptor/Ligand Interactions., PMID:31002602
• LLT1-CD161 Interaction in Cancer: Promises and Challenges., PMID:35185935
• A Role of NKR-P1A (CD161) and Lectin-like Transcript 1 in Natural Cytotoxicity against Human Articular Chondrocytes., PMID:29212911
• Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A., PMID:25826155
• CD161 (human NKR-P1A) signaling in NK cells involves the activation of acid sphingomyelinase., PMID:16455998
• Molecular basis for LLT1 protein recognition by human CD161 protein (NKRP1A/KLRB1)., PMID:21572041
• Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes., PMID:8077657
• Nkrp1 family, from lectins to protein interacting molecules., PMID:25690298
• Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction., PMID:27626681
• NKRP1A molecule is involved in transendothelial migration of CD4+ human T lymphocytes., PMID:9232437
NoteFor research use only. Not suitable for clinical or therapeutic use.
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