| Catalog No. | HT343066 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Isotype | Fusion - [ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)]2 - IGHG1 Fc (Fragment constant) |
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| Expression system | Mammalian Cells |
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| Target | GDF-8, GDF8, MSTN, Myostatin, Growth/differentiation factor 8 |
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| Concentration | 1.9mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | O14793 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1458°C. |
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| Alternate Names | ACE-031,ActRIIB-IgG1,ActRIIb:FcFusionProtein,HGT-4510,RAP-031,CAS:1169766-01-1 |
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| Background | Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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