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Research Grade Bintrafusp Alfa (HV974116)

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Spec:

100ug
1mg

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Overview
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References
Datasheet

Overview

Catalog No.	HV974116
Species reactivity	Human
Applications	Research Grade Biosimilar
Host species	Human
Isotype	IgG1-lambda
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, TGFR-2, TbetaR-II, TGF-beta type II receptor, TGFBR2, TGF-beta receptor type-2, TGF-beta receptor type II, Transforming growth factor-beta receptor type II
Concentration	1mg/ml
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G, purified from cell culture supernatant.
Accession	Q9NZQ7 & P37173
Form	Liquid
Storage buffer	0.01M PBS,pH7.4.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -1433°C.
Background	Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer.
Note	For research use only. Not for use in clinical or therapeutic applications.

Images

Bioactivity

SEC-HPLC detection for Research Grade Bintrafusp Alfa.

References

Datasheet

Research Grade Bintrafusp Alfa.pdf

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