| Catalog No. | CF977016 |
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| Species reactivity | Dog |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Caninized |
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| Isotype | IgG2, kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | TGFB1/TGF-beta-1 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P54831 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | ZTS00521426, ZTS-00521426, ZTS00521426, 2473240-98-9 |
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| Background | Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator.
• TGFB1 induces fetal reprogramming and enhances intestinal regeneration., PMID:37865088
• Biomarkers for the identification of cardiac fibroblast and myofibroblast cells., PMID:29987445
• Association between TGF-β gene polymorphism and myopia: A systematic review and meta-analysis., PMID:35905284
• A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis., PMID:38980870
• The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis., PMID:35525938
• Lack of association between the TGF-β(1) gene and development of COPD in Asians: a case-control study and meta-analysis., PMID:21556788
• TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years., PMID:32039767
• Direct effect of transforming growth factor-beta 1 (TGF-β1) on human apical papilla cell proliferation and mineralisation., PMID:34596309
• Concentration change of TGF -β 1 in aqueous humor of rabbits., PMID:24507648
• TGF-beta 1 codon 10 polymorphism is associated with cerebral SVD., PMID:22030425
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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