| Catalog No. | HY422026 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG4 |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | CD28, TP44, T-cell-specific surface glycoprotein CD28 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P10747 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | TGN1412, TAB08, TAB-08, CD28-SuperMAB, 906068-56-2 |
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| Background | HY-P990938 is an CD28-targeting Fab'-G1 -κ type chimeric antibody.
• Differential regulatory signals delivered by antibody binding to the CD28 (Tp44) molecule during the activation of human T lymphocytes., PMID:2964482
• The murine homologue of the T lymphocyte antigen CD28. Molecular cloning and cell surface expression., PMID:2157764
• Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti-CD28 and anti-CD2 monoclonal antibodies., PMID:3126073
• Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system., PMID:2825196
• Activation of T lymphocytes by immobilized monoclonal antibodies to CD3. Regulatory influences of monoclonal antibodies to additional T cell surface determinants., PMID:2452835
• Phosphorylation of T cell membrane proteins by activators of protein kinase C., PMID:3259610
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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