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Research Grade Anumigilimab (HV643016)

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Spec:
  • 100ug
  • 1mg
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Overview
Catalog No.HV643016
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetG-CSF receptor, CSF3R, GCSFR, G-CSF-R, CD114, Granulocyte colony-stimulating factor receptor
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionQ99062
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesCSL324, CSL-324, CSL324, G-CSFR2416593-08-1
BackgroundBalugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer.
• Characterization of G-CSF receptor expression in medulloblastoma., PMID:32642714
• Gene Expression of CSF3R/CD114 Is Associated with Poorer Patient Survival in Glioma., PMID:38474265
• CSF3R/CD114 mediates infection-dependent transition to severe asthma., PMID:30312710
• Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus., PMID:29868014
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Anumigilimab.

  • Bioactivity

    Detects CD114/CSF3R in indirect ELISAs.

  • SDS-PAGE

    SDS-PAGE for Research Grade Anumigilimab.

  • Flow CytoMetry

    Flow-cytometry using anti-human CD114 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD114 monoclonal antibody (Catalog: HV643016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

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