| Catalog No. | HB885016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Humanized |
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| Isotype | IgG2-kappa |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | Leukocyte-endothelial cell adhesion molecule 3, Platelet activation dependent granule-external membrane protein, Granule membrane protein 140, GMP-140, CD62P, SELP, GRMP, PADGEM, CD62 antigen-like family member P, LECAM3, P-selectin, GMRP |
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| Concentration | 6.06mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | P16109 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -621°C. |
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| Alternate Names | SelG1,CAS:1690318-25-2 |
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| Background | Crizanlizumab is an anti-P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). Crizanlizumab prevents vaso-occlusive crises (VOCs) and can be used for research of sickle cell disease. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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