Catalog No. | VK617016 |
---|---|
Species reactivity | Humanimmunodeficiencyvirus1(HIV-1) |
Applications | Research Grade Biosimilar |
Host species | Humanized |
Isotype | IgG1, kappa |
Expression system | Mammalian Cells |
Clonality | Monoclonal |
Target | env/Env polyprotein |
Concentration | 1mg/ml |
Endotoxin level | Please contact the lab for this information. |
Purity | >95% purity as determined by SDS-PAGE. |
Purification | Protein A/G, purified from cell culture supernatant. |
Accession | P03377 |
Form | Liquid |
Storage buffer | 0.01M PBS,pH7.4. |
Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -482°C. |
Alternate Names | KD-247,CAS:914257-21-9 |
Background | Suvizumab (KD-247) is an neutralizing antibody anti-HIV-1. Suvizumab effectively neutralizes HIV-1MN, HIV-1SF2 and HIV-189.6 with IC50 values of 0.1 µg/mL, 1.0 µg/mL and 0.2 µg/mL, respectively. Suvizumab reduces the viral load of HIV. Suvizumab has good tolerance and can be used to prevent HIV infection. |
Note | For research use only. Not for use in clinical or therapeutic applications. |
SEC-HPLC detection for Research Grade Suvizumab.
Detects env/Env polyprotein in indirect ELISAs.
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