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Research Grade Casirivimab (VK565046)

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  • 100ug
  • 1mg
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Overview
Catalog No.VK565046
Species reactivitySARS-CoV-2(2019-nCoV)
ApplicationsResearch Grade Biosimilar
Host speciesHuman
IsotypeIgG1, kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetSpike glycoprotein, S glycoprotein, E2, Peplomer protein, Spike protein S1, Spike protein S2, Spike protein S2', S, 2
Concentration1.7mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionP0DTC2
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -471°C.
Alternate NamesREGN-10933,REGN10933,CAS:2415933-42-3
BackgroundCasirivimab (REGN10933) is a human monoclonal antibody that targets the SARS-CoV-2 virus, which causes COVID-19. Casirivimab is ineffective against COVID-19 variants. Casirivimab can be used in combination with Imdevimab (HY-P99342), which alters the lung response of K18-hACE2 mice to the SARS-CoV-2 δ variant, effectively reducing viral load and improving symptoms.
NoteFor research use only. Not for use in clinical or therapeutic applications.
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  • Bioactivity

    SEC-HPLC detection for Research Grade Casirivimab.

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