| Catalog No. | HP458016 |
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| Species reactivity | Human |
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| Applications | Research Grade Biosimilar |
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| Host species | Humanized |
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| Isotype | Ig(G4-kappa_G4-lambda) |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | GPRC5D, G-protein coupled receptor family C group 5 member D, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
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| Concentration | 4.13mg/ml |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G, purified from cell culture supernatant. |
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| Accession | Q9NZD1 & P07766 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS,pH7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -445°C. |
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| Alternate Names | Bispecific,JNJ-64407564,CAS:2226212-40-2 |
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| Background | Talquetamab (JNJ-64407564) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab (JNJ-64407564) has antitumor activity. |
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| Note | For research use only. Not for use in clinical or therapeutic applications. |
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