| Catalog No. | HF974016 |
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| Species reactivity | Human |
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| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| Host species | Humanized |
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| Isotype | IgG1-nd |
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| Expression system | Mammalian Cells |
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| Clonality | Monoclonal |
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| Target | HLA class II histocompatibility antigen, DRB1 beta chain, Human leukocyte antigen DRB1, HLA-DRB1 |
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| Endotoxin level | Please contact the lab for this information. |
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| Purity | >95% purity as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Accession | P01911 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| Alternate Names | Hu1D10, 267227-08-7 |
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| Background | Apolizumab (Hu1D10) is a humanized monoclonal anti-Human leukocyte antigen-DR beta-chain antibody. Apolizumab can mediate apoptosis of chronic lymphocytic leukemia (CLL) cells in vitro.
• HLA common and well-documented alleles in China., PMID:30073798
• Association of Human Leukocyte Antigen (HLA) class II (DRB1 and DQB1) alleles and haplotypes with Rheumatoid Arthritis in Sudanese patients., PMID:37426636
• Human-leukocyte antigen class II genes in early-onset obsessive-compulsive disorder., PMID:28562177
• Association between human leukocyte antigen class II-DR-DQ and narcolepsy: a case control study., PMID:39150697
• Human leukocyte antigen class II (DRB1 and DQB1) alleles and haplotypes frequencies in patients with pemphigus vulgaris among the Serbian population., PMID:27072514
• Sarcoidosis and human leukocyte antigen class I and II genes: it takes two to tango?, PMID:15003948
• Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors., PMID:37114039
• A new strategy for systematically classifying HLA alleles into serological specificities., PMID:35538616
• Diagnosis of sarcoidosis., PMID:18664976
• Human leukocyte antigen class II alleles in Caucasian women with primary biliary cirrhosis., PMID:15713222
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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