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Research Grade Sibrotuzumab (HC440016)

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  • 100ug
  • 1mg
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Overview
Catalog No.HC440016
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetSurface-expressed protease, Gelatine degradation protease FAP, Integral membrane serine protease, Dipeptidyl peptidase FAP, Seprase, FAP, Post-proline cleaving enzyme, APCE, SIMP, FAPalpha, 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Serine integral membrane protease, Prolyl endopeptidase FAP
Concentration2.8mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionQ12884
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -419°C.
Alternate NamesBIBH1,CAS:216669-97-5
BackgroundSibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein (FAP). Sibrotuzumab can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC).
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SDS-PAGE

    SDS-PAGE for Research Grade Sibrotuzumab

  • SEC-HPLC

    SEC-HPLC detection for Research Grade Sibrotuzumab.

  • Bioactivity

    Detects Human FAP/FAPalpha in indirect ELISAs.

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