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Research Grade Tislelizumab (HS870066)

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  • 100ug
  • 1mg
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Overview
Catalog No.HS870066
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetProgrammed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Concentration3.3mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionQ15116
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -239°C.
Alternate NamesBGB-A317,CAS:1858168-59-8
BackgroundTislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma.
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • SEC-HPLC

    SEC-HPLC detection for Research Grade Tislelizumab.

  • Bioactivity

    Detects Human CD279/PDCD1/PD1 in indirect ELISAs.

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