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Research Grade Adebrelimab (HV974086)

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  • 100ug
  • 1mg
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Overview
Catalog No.HV974086
Species reactivityHuman
ApplicationsResearch Grade Biosimilar
Host speciesHumanized
IsotypeIgG4-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetB7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274
Concentration1mg/ml
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G, purified from cell culture supernatant.
AccessionQ9NZQ7
FormLiquid
Storage buffer0.01M PBS,pH7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -227°C.
Alternate NamesHTI-1088,SHR-1316,CAS:2247114-85-6
BackgroundAdebrelimab (SHR-1316) is a humanized IgG4 monoclonal PD-L1 (PD-1/PD-L1) antibody. Adebrelimab has promising antitumor activity in solid tumors including extensive-stage small-cell lung cancer (SCLC).
NoteFor research use only. Not for use in clinical or therapeutic applications.
Images
  • Bioactivity

    Detects CD274/PD-L1/B7-H1 in indirect ELISAs.

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