| Catalog No. | DY353048 |
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| Sample type | Plasma, Serum |
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| Sensitivity | 0.156 μg/ml |
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| Range | 0.31-5 μg/mL |
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| Accession | P08069 |
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| Applications | ELISA |
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| Detection method | Colorimetric |
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| Assay type | Quantitative |
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| Recovery | 80-120% |
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| Shipping | 2-8 ℃ |
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| Stability and Storage | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
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| Specifications | Ganitumab |
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| Alternate Names | AMG 479, CAS: 905703-97-1 |
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| Background | Ganitumab (AMG-479) is a mAb against IGF-IR which also inhibits binding of both IGF-1 and IGF-2 ligands to IGF-IR. The therapeutic value of AMG-479 was evaluated in several preclinical settings including androgen-dependent prostate cancer, and combined with androgen-deprivation therapy. Ganitumab was found to be most potent against VCaP xenografts when it was used in combination with complete androgen-deprivation therapy. After 4 weeks of treatment, tumor volume was reduced by 72% and growth suppression was maintained over 16 weeks of treatment. These findings suggested that the use of ganitumab in conjunction with androgen-deprivation therapy may be beneficial in the treatment of prostate cancer. |
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| Note | For Research Use Only. |
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