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Anti-Nivolumab Polyclonal Antibody (AS870024)

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Overview
Catalog No.AS870024
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
ClonalityPolyclonal
ImmunogenNivolumab
TargetRabbit polyclonal to Opdivo.
SpecificityThe product is specific for Nivolumab. This antibody serves as an excellent positive control for Nivolumab immunogenicity (ADA) assays.
PurificationPurified by antigen affinity column.
AccessionCAS: 946414-94-4
FormLiquid
Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundNivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Antibodysystem Anti-Nivolumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Nivolumab.
NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
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