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Anti-Pembrolizumab Polyclonal Antibody (AS870014)

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Overview
Catalog No.AS870014
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
ClonalityPolyclonal
ImmunogenPembrolizumab
TargetRabbit polyclonal to Keytruda.
SpecificityThe product is specific for Pembrolizumab. This antibody serves as an excellent positive control for Pembrolizumab immunogenicity (ADA) assays.
PurificationPurified by antigen affinity column.
AccessionCAS: 1374853-91-4
FormLiquid
Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundPembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Antibodysystem Anti-Pembrolizumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Pembrolizumab.
NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
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