Catalog No. | AB769014 |
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Applications | ELISA |
Host species | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Ustekinumab |
Target | Rabbit polyclonal to Stelara. |
Specificity | The product is specific for Ustekinumab. This antibody serves as an excellent positive control for Ustekinumab immunogenicity (ADA) assays. |
Purification | Purified by antigen affinity column. |
Accession | CAS: 815610-63-0 |
Form | Liquid |
Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
Stability and Storage | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
Background | Ustekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. Antibodysystem Anti-Ustekinumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Ustekinumab. |
Note | Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only. |
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