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Anti-Dupilumab Polyclonal Antibody (AB732014)

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Overview
Catalog No.AB732014
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
ClonalityPolyclonal
ImmunogenDupilumab
TargetRabbit polyclonal to Dupixent.
SpecificityThe product is specific for Dupilumab. This antibody serves as an excellent positive control for Dupilumab immunogenicity (ADA) assays.
PurificationPurified by antigen affinity column.
AccessionCAS: 1190264-60-8
FormLiquid
Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundDupilumab with trade name Dupixent, is an FDA-approved drug for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4Rα) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling. Anti-Dupilumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Dupilumab.
NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
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