Catalog No. | AY583024 |
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Applications | ELISA |
Host species | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Tocilizumab |
Target | Rabbit polyclonal to Actemra. |
Specificity | The product is specific for Tocilizumab. This antibody serves as an excellent positive control for Tocilizumab immunogenicity (ADA) assays. |
Purification | Purified by antigen affinity column. |
Accession | CAS: 375823-41-9 |
Form | Liquid |
Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
Stability and Storage | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
Background | Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann–La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects. |
Note | Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only. |
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