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Anti-Eculizumab Polyclonal Antibody (AF687014)

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Overview
Catalog No.AF687014
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
ClonalityPolyclonal
ImmunogenEculizumab
TargetRabbit polyclonal to Soliris.
SpecificityThe product is specific for Eculizumab. This antibody serves as an excellent positive control for Eculizumab immunogenicity (ADA) assays.
PurificationPurified by antigen affinity column.
AccessionCAS: 219685-50-4
FormLiquid
Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundEculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.
NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
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