Catalog No. | AF687014 |
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Applications | ELISA |
Host species | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Eculizumab |
Target | Rabbit polyclonal to Soliris. |
Specificity | The product is specific for Eculizumab. This antibody serves as an excellent positive control for Eculizumab immunogenicity (ADA) assays. |
Purification | Purified by antigen affinity column. |
Accession | CAS: 219685-50-4 |
Form | Liquid |
Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
Stability and Storage | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
Background | Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions. |
Note | Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only. |
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