Catalog No. | AT439014 |
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Applications | ELISA |
Host species | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Denosumab |
Target | Rabbit polyclonal to Prolia. |
Specificity | The product is specific for Denosumab. This antibody serves as an excellent positive control for Denosumab immunogenicity (ADA) assays. |
Purification | Purified by antigen affinity column. |
Accession | CAS: 615258-40-7 |
Form | Liquid |
Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
Stability and Storage | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
Background | Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface. |
Note | Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only. |
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