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Anti-Denosumab Polyclonal Antibody (AT439014)

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Overview
Catalog No.AT439014
ApplicationsELISA
Host speciesRabbit
IsotypeIgG
ClonalityPolyclonal
ImmunogenDenosumab
TargetRabbit polyclonal to Prolia.
SpecificityThe product is specific for Denosumab. This antibody serves as an excellent positive control for Denosumab immunogenicity (ADA) assays.
PurificationPurified by antigen affinity column.
AccessionCAS: 615258-40-7
FormLiquid
Storage buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and StorageThe product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
BackgroundDenosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface.
NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
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