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Research Grade Diridavumab
Overview
Catalog No. VK515016
Host species Human
Species reactivity Influenza A virus
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Purity >95% purity as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG1, lambda
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target HA/Hemagglutinin
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level Please contact the lab for this information.
Expression system Mammalian Cells
Accession P03455
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternative nameCR-6261, CR6261, 1393659-46-5
Note For research use only. Not suitable for clinical or therapeutic use.
Description

Diridavumab, the alternative name, CR6261, is a human monoclonal antibody directed against influenza A hemagglutinin. The CR6261 antibody was first discovered by the Scripps Institute and Crucell, a Dutch biopharmaceutical company, and later developed by Janssen Pharmaceutical Companies of Johnson & Johnson under the trade name diridavumab. Cr6261 is under investigation in clinical trial NCT02016066 (A Study to Assess the Safety, Pharmacokinetics and Immunogenicity of Diridavumab in Japanese Healthy Participants).

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Bioactivity
SEC-HPLC detection for Research Grade Diridavumab.

SDS-PAGE
SDS-PAGE for Research Grade Diridavumab.