Research Grade Glembatumumab
Overview
Catalog No.
HC358016
Host species
Human
Species reactivity
Human
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Purity
>95% purity as determined by SDS-PAGE.
Clonality
Monoclonal
Isotype
IgG2-kappa
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target
NMB, Hematopoietic growth factor inducible neurokinin-1 type, HGFIN, GPNMB, Transmembrane glycoprotein NMB
Purification
Protein A/G purified from cell culture supernatant.
Endotoxin level
Please contact the lab for this information.
Expression system
Mammalian Cells
Accession
Q14956
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternative name
CDX-011(DOX), CR011, glembatumumabvedotin(ADC), 1020264-78-1
Note
For research use only. Not suitable for clinical or therapeutic use.
Images
SEC-HPLC
SEC-HPLC detection for Research Grade Glembatumumab.
Bioactivity
Detects GPNMB in indirect ELISAs.
SDS-PAGE
SDS-PAGE for Research Grade Glembatumumab.
Flow CytoMetry
Flow-cytometry using anti-human GPNMB antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human GPNMB monoclonal antibody (Catalog: HC358016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.