Research Grade Mirvetuximab
Overview
Storage buffer
0.01M PBS, pH 7.4.
Purity
>95% purity as determined by SDS-PAGE.
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target
Folate receptor alpha, FOLR, FOLR1, Adult folate-binding protein, Folate receptor 1, FR-alpha, KB cells FBP, FBP, Ovarian tumor-associated antigen MOv18, Folate receptor, adult
Purification
Protein A/G purified from cell culture supernatant.
Endotoxin level
Please contact the lab for this information.
Expression system
Mammalian Cells
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternative name
M9346A, IMGN853, M9346A-sulfo-SPDB-DM4, 1453084-36-0
Note
For research use only. Not suitable for clinical or therapeutic use.
Images
SEC-HPLC
SEC-HPLC detection for Research Grade Mirvetuximab.
Bioactivity
Detects Human FOLR1 in indirect ELISAs.
Flow Cytometry
Flow-cytometry using anti-human FOLR1 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human FOLR1 monoclonal antibody (Catalog HB825026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE
SDS-PAGE for Research Grade Mirvetuximab.